Scientist II, Molecular Biology Gene Editing
Editas Medicine, United States
Job Description
At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.
We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.
Together, we are leading the way towards a healthier and more equitable future.
Position Summary
Editas Medicine is seeking an accomplished Scientist to join our Molecular Biology amp; Gene Editing group. This individual will support the design and execution of novel engineered gene editing technologies by leveraging their expertise in molecular biology techniques, such as plasmid design and various molecular cloning techniques. The Scientist will play a key role in evolving the current and next generation of gene editing platforms at Editas.
Requirements
Key Requirements
As the Scientist, Molecular Biology amp; Gene Editing, you will:
- Be part of a dedicated team to develop innovative gene editing platform technologies.
- Design and execute directed evolution and/or rational design processes to engineer gene editing technologies with desired properties, including precision genomic editing, whole gene knock-in, enhanced sequence-specific activity and specificity.
- Design and construct libraries using rational and combinational molecular biology methods.
- Develop in vitro or cell-based high throughput screening methods for functional readout.
- Build assays to quantify and measure efficacy and specificity of novel gene editing technologies in vivo and in vitro.
- Provide training, scientific and personnel management for junior team members.
Required Qualifications:
The ideal candidate will possess:
- Ph.D. in cell biology, molecular biology, bioengineering, or a related field
- 2+ years of industry experience in molecular biology or a related field
- Molecular biology expertise including plasmid design, molecular cloning techniques such as Gibson assembly and golden gate cloning, primer design, PCR, gel electrophoresis, DNA and RNA purification, qPCR, and RT-qPCR
- Extensive experience in mammalian cell culture, transfections, and cell-based assays
- Experience in protein structure/function study and protein engineering.
- Experience working with CRISPR, lentivirus, fluorescence microscopy and FACS
- Familiarity with DNA analysis software such as VectorNTI,Geneious,Benchling
Preferred Qualifications:
Additionally, candidates with the following attributes are preferred:
- Preferably knowledge in genetic diseases, gene editing and gene therapy.
- An ability to work in a fast-paced, team-oriented, multidisciplinary environment.
Benefits
Benefits Summary:
Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.
If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.
Fostering Belonging. Fueling Innovation. Transforming Lives.