Job Description
A cancer diagnosis is something no one wants to hear. Too often, cancer is detected late, once it has spread and treatment options are limited. But cancer can be more effectively treated with an intent to cure if caught in the earlier stages. At Thrive, an Exact Sciences Company, our goal is to transform this outlook: to catch cancer earlier, including several with no screening options today, to improve patient outcomes. We are developing a blood-based test that is designed to be affordable and utilized as part of routine medical care to detect multiple types of cancer at earlier stages. Our approach goes beyond a cancer diagnosis. We are developing a platform that will serve as a resource to help patients and their families maneuver the often confusing and overwhelming path that follows a cancer diagnosis.
At Thrive, we are motivated to change the face of a cancer diagnosis. We challenge the status quo and are willing to think differently. Our curiosity drives us. There are countless questions related to cancer, and we flourish by finding solutions. We know what we do is important, and we take our work seriously. We also have fun. We do our work with vibrant energy, and we laugh out loud at the little things. This is How We Thrive.
The RoleThe successful candidate will be responsible for contributing to the development and optimization of the genomic analytical assay component of impactful new diagnostic assays for early cancer detection. The successful candidate will partner with cross-functional, multi-site teams to support the development, tech transfer and deployment of internal and outsourced projects.Major Responsibilities· Develop, optimize, and validate genomic assays and apply to model and clinical samples.· Conduct bench experiments to develop and optimize assays on multiple clinical sample types (Serum, Plasma).· Contribute to feasibility, development, and validation of assays in regulated environments.· Present experimental results to collaborative development team.· Provide technical input and participate on decisions impacting experimental design and project planning. Contribute ideas to improve methods and processes.· Operate scientific instrumentation, including lab automation and NGS sequencers in a research use only setting.· Work with external CROs for sample procurement, receipt, and QC for development and validation studies.
Requirements and Qualifications· MSc or PhD in cell/molecular biology, genetics, cancer biology, or a related discipline.· 2+ years of experience working in an academic or industry lab, with a proven track record of hands-on experience working successfully with clinical samples.· Experience in optimizing NGS and associated methods including DNA-seq, RNA-seq, and Methylation sequencing on clinical samples.· Ability to troubleshoot technical and scientific issues, both individually and as part of a team.· Excellent collaboration, organizational, and documentation skills.· Strong communication skills for the purpose of effective contribution to multi-site collaborations both within the business unit and with external vendors, CROs, and biopharma.· Experience with automation platforms (Hamilton, Tecan, Bravo, etc.) a plus.· Experience or interest in learning protein immunoassay techniques.Thrive Earlier Detection is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
TO ALL AGENCIES:Please, no phone calls or emails to any employee of Thrive about our openings. All resumes submitted by search firms/employment agencies to any employee at Thrive via email, the internet or in any form and/or method will be deemed the sole property of Thrive, unless such search firms/employment agencies were engaged by Thrive for this position and a valid agreement with Thrive is in place. In the event a candidate who was submitted outside of the Thrive agency engagement process is hired, no fee or payment of any kind will be paid.
Job Specification