Scientist, Immunology
BlueRock Therapeutics, United States
Job Description
Who is BlueRock?
BlueRock Therapeutics, a wholly-owned and independently operated subsidiary of Bayer AG, is a leading engineered cell therapy company using its unique CELL+GENE platform to direct cellular differentiation and genetically engineer cells to create a new generation of cellular medicines that address large patient populations suffering from neurological, cardiovascular, and immunology diseases.
The convergence of cell biology and genetic engineering is creating fundamental new ways to impact disease. Founded in 2016 to capitalize on these technological breakthroughs, we are advancing our novel CELL+GENE platform to develop, manufacture, and deliver an entirely new generation of authentic and engineered cell therapies across three therapeutic areas: neurology, cardiology, and immunology.
What Are We Doing?
Our foundational science harnesses the ability to create and then direct the differentiation of universal pluripotent stem cells into authentic, functional cells that can be used as allogeneic cellular therapies to treat a broad array of diseases. We can also further engineer these cells, enabling them to produce enzymes, antibodies, and other proteins for additional therapeutic benefit.
We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options.
We are seeking individuals who are collaborative, thrive in a fun and dynamic culture, and are steadfast in the commitment to advance cutting-edge cellular therapies to impact patients’ lives.
Description of Position:
BlueRock Therapeutics is seeking a highly motivated Scientist for our Immunology team in Cambridge, MA. The successful candidate will have strong expertise in Immunology and T cell or innate immune cell biology and is expected to play an integral role in the team. Reporting to the VP Immunology, this individual will engineer novel immune cell therapies derived from induced Pluripotent Stem Cells (iPSC) for the treatment of inflammatory or autoimmune diseases. This is an exciting and challenging opportunity to contribute to bringing a new class of cellular therapies to patients with inflammatory or autoimmune diseases using our unique CELL+GENE platform.
Responsibilities:
- Conceive, design and perform experiments independently for proof of concept studies
- Direct and oversee the work of Research Associates or contract research organizations (CRO) as necessary
- Generate, analyze and document scientific data; present the results to internal and external stakeholders
- Assist company in securing IP from research discoveries
Minimum Requirements:
- Minimum of a Ph.D. in immunology or a related discipline
- Minimum of 1 year of postdoctoral training in immunology (immune tolerance, inflammation or autoimmunity) is required; 1-3 years of this training is preferred
- In-depth knowledge of immunology and/or autoimmunity literature is required
- Proficiency in immunological assays to assess T cell or innate immune cell phenotype and function in vitro and/or in animal models of inflammatory or autoimmune diseases is required
- Strong experience in primary immune cell culture and analysis by multi-color flow cytometry is preferred
- Experience in molecular biology and genome editing (CRISPR/Cas9) is a plus
- Self-motivated, scientifically rigorous, strong problem-solving and analytical skills
- Ability to work independently and within a cross-functional team in a results-oriented research environment
- Effective communication and interpersonal skills
Working Environment:
- In this position you will work in a controlled laboratory environment
- You may be periodically required to move heavy equipment up to 50lbs
- There is a risk of potential exposure to chemicals and biohazards
- Working in the laboratory requires mandatory use of personal protective equipment
Equal Opportunity Workplace: At BlueRock, we welcome and support differences and diversity and we are proud to be an equal opportunity workplace. Please let us know if you require disability-related accommodation or other grounds protected by human rights legislation during the recruitment process so that we can work with you to meet your needs.