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Research Associate - Cancer Biology Drug Discovery Job in United States
Monte Rosa Therapeutics , United States

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Experience
1 Year
Salary
0 - 0
Job Type
Job Shift
Job Category
Requires Traveling
No
Career Level
Telecommute
No
Qualification
Master's Degree
Total Vacancies
1 Job
Posted on
Apr 3, 2021
Last Date
Jul 3, 2021
Location(s)

Job Description

We are seeking an energetic and self-motivated research associate to join a team of scientists working towards the discovery of unique anti-cancer compounds for the treatment of targeted patient populations. Role requires prior experience with cell/molecular biology amp; drug discovery.

Principal Duties and Responsibilities

Validate hits from high-throughput screens using medium-throughput plate based cellular assays.

Independently perform viability assays, western blotting, and/or flow cytometry/FACS to analyze effect of small molecules on viability and/or reporter expression.

Perform cellular and molecular assays to define mechanism of action for compounds and/or PD/efficacy relationships.

Participate in team drug discovery efforts to select lead candidate molecules and transition into clinical development.

Independently design, interpret, document and present research findings at internal meetings

Requirements

BS/MS in cell/molecular biology, cancer biology or genetics with at least 1 year hands-on experience in drug discovery preferably in a pharmaceutical setting.

Previous work with culture and maintenance of mammalian cell lines, including transfection and transduction techniques, as well as stable cell line generation. Experience working with Incucyte Systems preferred.

Prior experience preparing drug dilutions and performing drug sensitivity experiments and/or establishing target engagement/PD/efficacy relationships.

Experience with molecular biology methods and assays such as molecular cloning, RNA and protein expression approaches (e.g. QPCR, Western blotting, immunoprecipitation).

Ability to maintain timely and detailed experimental records using an electronic lab notebook.

Experience using Microsoft Excel, Powerpoint and GraphPad Prism. Spotfire software experience a plus.

Excellent interpersonal skills and willingness to learn a variety of new techniques and technologies.

Job Specification

Monte Rosa Therapeutics

Information Technology and Services - Basel, Switzerland