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Senior Scientist, Proteomics - Molecular Degraders Job in United States
Monte Rosa Therapeutics , United States

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1 Year
0 - 0
Job Type
Job Shift
Job Category
Requires Traveling
Career Level
Total Vacancies
1 Job
Posted on
Apr 3, 2021
Last Date
Jul 3, 2021

Job Description

Monte Rosa Therapeutics is seeking a highly skilled and motivated Proteomics Senior Scientist with drug discovery experience to join its growing Proteomics global team. This is an exciting opportunity to join a team responsible for the characterization of novel small molecule glue-based degraders to support Monte Rosa’s growing pipeline. The successful candidate will be responsible for building out Proteomics operations in Boston, providing both scientific leadership and hands-on technical expertise. The candidate should exhibit excellent communication and collaborative skills for working on cross-functional multi-disciplinary drug discovery teams and have experience managing direct reports.

Principal Duties and Responsibilities:

Responsible for the implementation and development of the Proteomics platform in Boston

Responsible for independently performing TMT quantitative proteomics experiments from sample preparation, LC-MS/MS, to data analysis, interpretation, and presentation of the proteomics results

Collaborate on projects with multi-disciplinary teams involving Biologist, Chemist, and Data scientists

Evaluate and implement new technologies/methodologies that may enhance proteomic workflows

Report data, interpret results, and present at project team meetings.


Ph.D. in analytical chemistry, biochemistry, or related field

At least 5 years’ experience in proteomics in Pharma, Biotech or equivalent

Extensive hands-on experience in TMT quantitative proteomics methodology

Hands-on experience in protein post-translational modification analysis, protein-protein-interaction analysis, and targeted mass spectrometry analysis would be an advantage

Hands-on experience and strong troubleshooting skills for HPLC and orbitrap mass spectrometer instrument

Experience in processing proteomics data, with Mascot, Proteome Discoverer, Maxquant, Skyline, Scaffold

Excellent communication, data presentation and visualization skills both verbally and in writing

Highly collaborative and able to work in a matrix-type, interactive, and fast-paced drug discovery environment

Job Specification

Monte Rosa Therapeutics

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