Scientist I/Development Lead: Sequencing Team

Scientist I/Development Lead: Sequencing Team
Editas Medicine, United States

Experience
1 Year
Salary
0 - 0
Job Type
Job Shift
Job Category
Traveling
No
Career Level
Telecommute
No
Qualification
Doctorate
Total Vacancies
1 Job
Posted on
Apr 28, 2021
Last Date
May 28, 2021
Location(s)

Job Description

We are looking for a highly motivated and creative person to join the Sequencing Team. The Scientist I will consult with scientific teams to discuss assay development need. Together with the Assoc. Director, the Development Lead will outline the development approach and timelines for assay development. This person will work with the scientific teams to coordinate assay validation. Once validated, the candidate will work with the Sequencing Production Team and to transition new assays into a high-throughput production process. A deep understanding on Next Generation Sequencing Technologies will be essential to successfully execute this objective.

The candidate will also work with the CompBio and Informatics teams to build LIMS tools to track process performance, capture data and establish performance metrics and develop new analysis pipelines to create a streamlined and robust sequencing platform.

Key Responsibilities:

  • Candidate will be a team expert on the latest state of the art sequencing technologies
  • Sequencing consultant for novel assay development
  • Experience with Illumina, Oxford Nanopore and PacBio technologies
  • Extensive library prep experience: Nextera library prep, RNA-seq (short and long read), Custom Hybrid Selection designs, Cas9 Targeted Sequencing, rhAmpSeq multiplex panels
  • Interact directly with the CompBio team to develop custom analysis pipelines for new assays
  • Work with the Informatics and Sequencing Production team to automate process and track samples and sequencing data
  • Present new methodology and results to leadership team and company scientific meetings
  • Maintain and update ELN
  • Summarize data into study reports.
  • Keep up with the literature on new sequencing methods and technologies
  • Will manage a direct report

Requirements

Minimum Requirements

  • PhD degree in molecular biology or related field
  • 2-3+ years hands-on method development and library prep experience for Next Generation Sequencing (NGS) technologies
  • Experience with automation is a plus: Beckman FX, Labcyte Echo, and the MANTIS liquid handler
  • Experience working in a high-throughput sequencing environment desired
  • Ability to perform with versatility in a high paced environment
  • Self-motivated, highly skilled and capable of working independently to drive assignment to completion, well-organized with attention to details, analytical and results-oriented
  • Excellent presentation skills
  • Excellent troubleshooting skills

Job Specification

Job Rewards and Benefits

Editas Medicine

Information Technology and Services - Cambridge, United States
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