Scientist I/II, Lead Discovery - Clinical Cell Line Engineering
Editas Medicine, United States

Key Responsibilities amp; Accountabilities:

• Develop and advance the iPSC Engineering Platform for the generation and selection of genetically engineered iPSC clones
• Lead the generation of master cell banks to be used to produce clinical material adhering to GMP principles
• Maintain close interactions with the iPSC expansion and differentiation teams as well as CMC/manufacturing, and QA/QC groups
• Participate in efforts with external collaborator projects
• Create, analyze, and present on results and make recommendations to therapeutic project teams, external collaborators, and senior leadership
• Stay current with the iPSC literature, external competitors, and the global scientific community, especially as it relates to cell-based therapeutic development

Requirements

Knowledge, Skills amp; Capabilities:

• Experience with mammalian Cell Line Development, master cell bank creation for biologics production (eg CHO, HEK293, etc), cell-based therapies (eg: iPSC, healthy donor allogenic), or similar therapeutic applications
• Familiarity with cellular engineering, not necessarily CRISPR/CAS, but genetically modifying cell lines, clonal isolation, and screening
• Experience with CMC/manufacturing, Cell Line Development and clean room operations
• Experience leading scientific and technical teams
• Strong background and scientific acumen demonstrated by education, publications, career progression, and accomplishment

Education amp; Relevant Work Experience:

• PhD or advanced degree in cell biology, molecular biology, or related field, with greater than 1-3 years of industry experience

Job Rewards and Benefits