Senior Research Associate, Process and Analytical Development
Editas Medicine, United States

Key Responsibilities amp; Accountabilities:

• Work collaboratively with Research to assist with transfer of assays into AD.
• Perform assay development and optimization.
• Collaborate with PD to generate data to support formulation studies, stability studies, and characterization of drug substance and/or drug product.
• Document all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner.
• Compile and present data and assist in authoring and reviewing of test methods, technical reports, and supporting procedures.
• Assist in the technical transfer of assays to Quality Control or central testing laboratories.
• Support testing of reference standards, lead stability samples, forced stability samples, toxicology lots, non-human use (NHU) engineering runs, and clinical manufacturing runs, as appropriate.
• Cross-train personnel on assays, as required, and provide guidance to junior research associates.
• Other responsibilities as required.

Requirements

Knowledge, Skills amp; Capabilities:

• Experience with applicable protein, RNP, and/or AAV analytical methods. This includes biophysical experience in methods such as HPLC/UHPLC assays, CE-SDS, SDS PAGE experience with molecular techniques such as ddPCR/qPCR, ELISA, and cell-based assays will also be helpful.
• Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment.
• Strong verbal and written communication skills.
• Knowledge of CRISPR/Cas9 gene editing technologies.
• Development and/or technical transfer of GMP test methods for biologics.

Education amp; Relevant Work Experience:

• Bachelor’s experience in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 5+ years of relevant experience or Master’s with 2 years of experience.

Job Rewards and Benefits