Associate / Sr Associate Scientist, Downstream Process Development
Generation Bio, United States
Job Description
Generation Bio is a biotechnology company leading a new generation of gene therapy. With our proprietary re-dosable ceDNA technology, we are expanding the reach of gene therapy. At Generation Bio, our goal is to bring the life-saving benefits of gene therapy to more people, living with a broader range of diseases, in more places around the world. Our vision is to make the ravages of genetic disease as imaginary to the next generation as polio feels to children today.
We are a thriving, collaborative, creative community of diverse talents, beliefs, and experiences relentlessly dedicated to our mission. Founded and launched by Atlas Venture. Headquartered in Cambridge, Massachusetts. Committed to a future where more people can live full lives.
Delve further. Please visit www.generationbio.com or follow @generationbio.
SUMMARY
Generation Bio seeks an enthusiastic and highly motivated Scientist to join the Process Research team to work on developing and improving downstream processes. The successful candidate will work in a multi-disciplinary team to assist in developing and implementing innovative downstream processes. Candidates with proven downstream process development experience will be highly valued, and curiosity and adaptability are required. This will be a key role in a dynamic, innovative team.
RESPONSIBILITIES:
Primary responsibilities for this role include:
- Directly assist in the planning and execution of laboratory experiments to develop downstream process for the purification of closed ended DNAs
- Execute experiments and collaborate efforts related to the development of downstream process steps including cell lysis, depth filtration, TFF, and chromatography steps
- Analyze process intermediates and final samples from the experiments
- Keep good records and updated electronic notebook for all executed experiments.
- Prepare, analyze, and present data internally to cross functional teams.
QUALIFICATIONS
- BS in Biochemistry, Bioengineering, Biotechnology, or related discipline
- Experience with downstream techniques such as depth filtration, FPLC and TFF
- Attention to detail and critical thinking
- Strong collaboration and team working skills
- Knowledge of cGMP, FDA and USP guidelines practices is a plus.
POSITION:?Full Time, Exempt
EEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.