Genomic Research Expert Lead (Data Science)
SOPHiA GENETICS, United States

In our journey to impact on patients' lives, we are looking for a Genomic Research ExpertLead to join the Data Science department of SOPHiA GENETICS in Boston, USA.

Reporting directly to the Chief Scientific Officer, you will play a leading role in the research and early development of cutting-edge computational workflows to detect diverse types of molecular alterations from clinical genomic data.

As a Genomic Research Expert Lead, you will contribute to the full product lifecycle. Your research responsibilities will include exploring how technical factors affect NGS assay performance, using these scientific insights (combined with biological expertise) to improve reagents and bioinformatics workflows and design prototype products. You will encounter DNA and RNA data obtained using targeted, whole exome, transcriptome or whole genome sequencing, and projects may lead to conference presentations, patents or research publications. You will also participate in product development, working closely with algorithm, software, systems engineering and commercial teams to transform early concepts into the next generation of SOPHiA GENETICS products. In this context, your roles will include project planning and leadership, pipeline and reagent development, product testing and performance evaluation. This is an exciting opportunity that will enable you to play a major part in our mission to help patients through delivering deep genomic insights.

Requirements

• Six years or more industry/academic experience in the field of genomics at PhD level or above.
• Demonstrated publication record in the field of genomics.
• Demonstrated record of leading scientific/development projects.
• Deep knowledge of human genome/transcriptome features and analytical workflows (e.g. SNV/indel/fusion detection or transcriptome profiling).
• Deep knowledge of DNA/RNA assay technologies (e.g, experience in different type of targeted enrichment NGS assays.).
• Expertise in data exploration and visualization using R, Python or equivalent.
• Creative and scientific mindset; able to tackle complex analytical or technical challenges.
• Solid understanding of genomic technologies and genomic biology.
• Highly motivated and able to work in a fast-paced, multidisciplinary and collaborative environment.
• Regulatory product development experiences is preferred.
• Deep medical experience in any genomics related disease is preferred.

Benefits

• Career opportunities in a fast-growing company with worldwide reputation
• A flexible and friendly working environment with a collaborative atmosphere
• An exciting company mission that brings together science and technology to directly impact the lives of patients with life threatening illness.
• A fast-growing company with plenty of opportunity for personal growth and development

Start: ASAP (or as agreed)

Contracttype: permanent full-time

Application process

If you think you fit this position, please send a CV and a cover letter. Please note that incomplete applications will not be considered.

After an initial screening process, candidates will be invited for remote interviews. Selected candidates will then be invited for personal interviews.

Job Rewards and Benefits