Principal Associate/Scientist Upstream Process Development
Generation Bio is an innovative genetic medicines company focused on creating a new class of non-viral gene therapy to provide durable, redosable treatments for people living with rare and prevalent diseases. The company’s non-viral platform incorporates a proprietary, high-capacity DNA construct called closed-ended DNA, or ceDNA; a cell-targeted lipid nanoparticle delivery system, or ctLNP; and an established, scalable capsid-free manufacturing process. The platform is designed to enable multi-year durability from a single dose of ceDNA and to allow titration and redosing if needed, and our scalable manufacturing process supports our mission to extend the reach of gene therapy to more people, living with more diseases, in more places around the world. Our vision is to make the ravages of genetic disease as imaginary to the next generation as polio feels to children today.
We are a thriving, collaborative, creative community of 120 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts.
Delve further. Please visit www.generationbio.com or follow @generationbio.
SUMMARY
Generation Bio seeks an enthusiastic and highly motivated Scientist to join the Production and Process Research (PPR) department within our organization. The PPR group focuses on exploring and developing new, innovative technologies for the continual improvement of our ceDNA production processes for yield gains, scalability, and robustness. This position will drive early-stage development efforts focused on the production of synthetic ceDNA gene therapy molecules. This role will have high visibility in a company that is expanding to support a dynamic pipeline.
RESPONSIBILITIES:
Primary responsibilities for this role include:
QUALIFICATIONS:
Desired experience:
POSITION: Full-Time, Non-Exempt
EEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.