Scientist/Sr Scientist Immunology/Cancer Biology
Location: Cambridge, MA
Job Code SCIIOB-20-2021
We are seeking a highly motivated and enthusiastic scientist to support Monte Rosa Tx effort to identify small molecule glue degraders in different disease areas such as cancer and autoimmune/inflammatory diseases. In this position within the Target Biology and Translational Research group, the candidate will provide scientific insight for the identification and validation of targets to support indication selection and early clinical development of novel molecular glue degraders. This energetic and self-motivated PhD scientist to join a team of scientists working towards discovery of unique molecular glue degraders for the treatment of targeted patient populations. The candidate will be a highly creative immunologist or cancer biologist with a strong desire to succeed at the highest level.
Principal Duties and Responsibilities
Independently design, execute and interpret cell-based experiments to optimize compound selection and explore therapeutic potential of drug targets
Design and develop cell and molecular assays to define mechanism of action for compounds, identify pharmacodynamic assays for utility in pre-clinical and clinical setting and test patient selection strategies
Identify pharmacodynamic assays for utility in pre-clinical and clinical setting; define PK/PD/efficacy relationships and test patient selection strategies
Utilize literature and internal genomics data sets to design and test hypothesis for drug targets
Interpret, present and report research findings at internal meetings and external scientific conferences
Requirements
Job Qualifications: