Senior/Principal Research Associate, Cell Biology
Editas Medicine, United States
Job Description
What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases.
We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.
Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.
Editas Medicine is seeking a highly motivated Senior / Principal Research Associate to join our ophthalmology discovery group. In this role you will contribute to the development of novel cell-based assays and ex vivo methods to evaluate the extent and effects of gene editing. An ideal candidate should have a background in cell culture, molecular biology, a track record of creative thinking, and a strong interest in genome editing. The successful candidate will be part of a dynamic, multidisciplinary discovery team dedicated to the development of gene editing-based therapies for genetically treatable ocular diseases.
Key Responsibilities:
- Development and optimization of cell-based assays
- Perform DNA/RNA extraction and qPCR, ddPCR, Western blot, and ELISA
- Perform ex vivo tissue dissection and isolation of cells and DNA/RNA from tissue
- Analyze and present data within the organization
- Share responsibility in maintaining lab equipment and reagent inventory
- Maintain an electronic lab notebook and contribute to supporting documentation
Requirements
Requirements:
- BS and 4-7 years or MS and 3 years in cell biology or related field with 4+ years of laboratory experience preferably in the biotechnology or pharmaceutical industry
- (Required) Experience with mammalian cell culture, including primary cells
- (Required) Proficient in molecular biology techniques, such as western blot, qPCR and ddPCR
- (Preferred) Experience developing and validating immunoassays (immunofluorescence and ELISA)
- (Preferred) Expertise in tissue dissection, experience performing microdissection, isolation of DNA/RNA from tissue
- (Preferred) Familiarity with microscopy, including high content imaging
- Experience troubleshooting assays, including consulting the literature for potential precedent
- Results-driven with excellent attention to details and ability to independently execute protocols
- Excellent written and oral communication skills
- Ability to work in a team-oriented, multidisciplinary environment