Senior Research Associate, Cellular Process Development
Editas Medicine, United States
Job Description
What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.
Key Responsibilities amp; Accountabilities:
- Work collaboratively with Research to transfer processes into PD.
- Perform process development and optimization.
- Collaborate with AD to generate data to support formulation studies, stability studies, and characterization of drug substance and/or drug product.
- Document all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner. Ensure any direct reports complete eLN entries in a timely manner.
- Compile and present data and assist in authoring and reviewing of batch records, work instructions, technical reports, and supporting procedures.
- Assist in the technical transfer of processes to Manufacturing or contract manufacturing organizations.
- Support the generation of reference standards, lead stability samples, forced stability samples, toxicology lots, non-human use (NHU) engineering run lots, and clinical manufacturing run lots, as appropriate.
- Cross-train personnel on processes, as required, and provide guidance to junior research associates.
- Other responsibilities as required.
Requirements
Knowledge, Skills amp; Capabilities:
- Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment.
- Strong verbal and written communication skills.
- Knowledge of CRISPR/Cas9 gene editing technologies.
- Primary cell experience preferred.
- Development and/or technical transfer of GMP processes for biologics.
Education amp; Relevant Work Experience:
- Bachelor’s experience in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 5+ years of relevant experience or Master’s with 2 4 years of experience.
- Experience with cellular processes, specifically adherent cell culture.