Senior Scientist
HistoWiz, United States

HistoWiz is the largest online histopathology company based in New York City. Our mission is to help biomedical researchers find cures by accelerating histopathology and enabling global collaboration. We are looking for a Senior Scientist interested in joining us in our mission and making an impact in the scientific community.

Since inception in 2013, we have doubled our month-over-month sales, driven primarily by customer referrals. We are profitable, won numerous awards and are funded by prestigious investors, including Y-Combinator and Zhenfund. We are seasoned scientists with experience at leading academic institutions and have published high impact research in top journals of biomedicine.

HistoWiz has over 1,000 paying customers globally from top academic institutions (e.g. MSKCC, Harvard, Stanford, HHMI) and pharmaceutical companies (e.g. CRISPR, Johnson amp; Johnson, Regeneron). We process tissue specimens and digitize all of the results, hosting our client’s data on a proprietary platform, PathologyMapTM . This platform not only enables industry-leading turnaround time for diagnosis, but also online viewing, sharing and search.

Requirements

We are looking for a highly motivated Senior Scientist to join our team. You will apply your expertise and skill in tissue-based advanced staining assays (immunohistochemistry, immunofluorescence, and in-situ hybridization) to support the day to day operations of the Department, maintain high levels of quality control as well as help expand the products and services that we offer. You will also work closely with our IHC team to coordinate the completion of orders and communicate with our top clients in designing their projects.

This role is ideal for a team player who is ready for a lot of responsibility and problem-solving in a fast-paced environment. The candidate should be able to prioritize tasks efficiently, work independently, as well as collaborate with our team of engineers, pathologists, technicians and senior management to achieve Company milestones.

Responsibilities:

• Research and review literature to find the best antibodies for IHC and IF
• Perform IHC, IF and RNAScope
• Oversee and perform biomarker and equipment validations
• Troubleshoot quality issues and work with pathologists to QC slides
• Communicate with our clients on a scientific level regarding their needs
• Develop new protocols and assays
• Coordinate in ordering supplies and maintain inventory for the IHC department
• Write IHC validation reports for pharma clients
• Maintain and write Standard Operating Procedures
• Design experiments and interpret results, while thinking critically about research projects
• Participate in project update meetings with clients
• Maintain accurate work records and document all progress in our Laboratory Information Systems
• Maintain laboratory organization and team priorities to complete projects with client-expected turnaround time.
• Design and recommend processes, systems, and operational changes to increase efficiency and effectiveness
• Attend conferences, give presentations and network within the scientific community
• Apply for grants and publish as needed

Requirements:

• PhD in scientific field (e.g. cancer biology, neuroscience, immunology)
• 3+ years experience with animal models of human disease
• First-authored publications in peer-reviewed journals or funded grants
• Experience optimizing antibody conditions and troubleshooting IHC/IF assays
• Experience with multiplex IHC/IF assays a plus
• Excellent communication skills and works well in a team environment
• Experience in project management and working with pathologists
• Experience planning, developing protocols, executing and writing reports for histology studies

A Plus:

• Experience with Leica Biosystems Bond autostainer and ISH
• IHC assay development experience in Pharma/Biotech
• Experience in QC and image analysis using automated software such as HALO

Benefits

• 100% coverage on employee health, vision and dental insurance, partial coverage for family
• Parental leave
• NY Commuter benefits
• Flexible Spending Accounts (FSA)
• Retirement planning (401k)
• 3 weeks PTO
• Team building events outside of the office

Job Rewards and Benefits